Prelims 2023 · Science and Technology · Question 80
'Microsatellite DNA' is used in the case of which one of the following?
Answer
Studying the evolutionary relationships among various species of fauna
- (a) Studying evolutionary relationships among fauna — Correct. Microsatellite DNA (short tandem repeats/SSRs) is highly polymorphic and is widely used in population genetics, DNA fingerprinting, and phylogenetic/evolutionary relationship studies.
- (b) Stimulating stem cells into tissues — Incorrect. Stem-cell differentiation is driven by growth factors, signaling pathways, and gene regulation, not by microsatellite DNA as a tool.
- (c) Promoting clonal propagation of horticultural plants — Incorrect. Clonal propagation is done through tissue culture/vegetative methods; microsatellite markers may help in genetic identification, not propagation itself.
- (d) Assessing drug efficacy in trials — Incorrect. Drug efficacy is assessed through clinical/pharmacological trials and biostatistics; microsatellite DNA is not the standard tool for this purpose.
Answer: (a)