Civil Services Prep

Prelims 2023 · Science and Technology · Question 80

'Microsatellite DNA' is used in the case of which one of the following?

  1. Studying the evolutionary relationships among various species of fauna
  2. Stimulating 'stem cells' to transform into diverse functional tissues
  3. Promoting clonal propagation of horticultural plants
  4. Assessing the efficacy of drugs by conducting series of drug trials in a population

Answer

Studying the evolutionary relationships among various species of fauna

  • (a) Studying evolutionary relationships among faunaCorrect. Microsatellite DNA (short tandem repeats/SSRs) is highly polymorphic and is widely used in population genetics, DNA fingerprinting, and phylogenetic/evolutionary relationship studies.
  • (b) Stimulating stem cells into tissuesIncorrect. Stem-cell differentiation is driven by growth factors, signaling pathways, and gene regulation, not by microsatellite DNA as a tool.
  • (c) Promoting clonal propagation of horticultural plantsIncorrect. Clonal propagation is done through tissue culture/vegetative methods; microsatellite markers may help in genetic identification, not propagation itself.
  • (d) Assessing drug efficacy in trialsIncorrect. Drug efficacy is assessed through clinical/pharmacological trials and biostatistics; microsatellite DNA is not the standard tool for this purpose.

Answer: (a)

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